3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine
Fmoc-.beta.-cyclopropyl-D-Ala-OH
CAS: 170642-29-2
Molecular Formula: C21H21NO4
3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine - Names and Identifiers
| Name | Fmoc-.beta.-cyclopropyl-D-Ala-OH |
| Synonyms | Fmoc-D-Cyclopropylalanine FMOC-D-CYCLOPROPYLALANINE FMOC-D-ALA(3-CYCLOPROPYL) Fmoc-(R)-3-Cyclopropylalanine FMOC-BETA-CYCLOPROPYL-D-ALA-OH FMOC-BETA-CYCLOPROPYL-D-ALANINE FMOC-D-ALA(BETA-CYCLOPROPYL)-OH Fmoc-.beta.-cyclopropyl-D-Ala-OH N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-CYCLOPROPYL-D-ALANINE 3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-CYCLOPROPYL-D-ALANINE (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclopropylpropanoic acid |
| CAS | 170642-29-2 |
| InChI | InChI=1/C21H21NO4/c23-20(24)19(11-13-9-10-13)22-21(25)26-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,13,18-19H,9-12H2,(H,22,25)(H,23,24)/t19-/m0/s1 |
3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine - Physico-chemical Properties
| Molecular Formula | C21H21NO4 |
| Molar Mass | 351.4 |
| Density | 1.291±0.06 g/cm3(Predicted) |
| Melting Point | 155 - 157°C |
| Boling Point | 583.5±33.0 °C(Predicted) |
| Flash Point | 306.7°C |
| Solubility | DMSO (Sligthly, Sonicated), Ethanol (Slightly, Sonicated), Methanol (Slightly, S |
| Vapor Presure | 1.85E-14mmHg at 25°C |
| pKa | 3.89±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.621 |
3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine - Risk and Safety
| HS Code | 29225090 |
3-cyclopropyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine - Introduction
An Fmoc-.beta.-cyclopropyl-D-Ala-OH is a chemical compound that has the following properties:
1. Appearance: white or white solid.
2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethylformamide.
3. Storage conditions: should be stored in dry, dark and low temperature environment.
The main use of Fmoc-.beta.-cyclopropyl-D-Ala-OH is as a protecting group and additive in peptide synthesis. It can be used as a protecting group for amino acids, protecting their activity in order to control the reaction during the synthesis. In addition, it can also be used as a C- terminal modification group to adjust the synthetic peptide chain to change its solubility and hydrophilicity.
The method of preparing Fmoc-.beta.-cyclopropyl-D-Ala-OH is generally obtained by chemical synthesis. Specific steps include reacting L-cyclopropylalanine with Fmoc-chloride to form Fmoc-.beta.-cyclopropyl-D-Ala-OH. The synthesis process requires safe operation, avoiding contact with skin and inhalation of harmful gases.
When using Fmoc-.beta.-When cyclopropyl-D-Ala-OH, certain safety precautions should be followed, including wearing personal protective equipment (such as laboratory gloves and face masks), ensuring that the operating area is well ventilated, and following correct operating procedures. In addition, the compound may cause harm to the environment, so appropriate disposal methods should be adopted when disposing of waste to meet environmental protection requirements.
1. Appearance: white or white solid.
2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethylformamide.
3. Storage conditions: should be stored in dry, dark and low temperature environment.
The main use of Fmoc-.beta.-cyclopropyl-D-Ala-OH is as a protecting group and additive in peptide synthesis. It can be used as a protecting group for amino acids, protecting their activity in order to control the reaction during the synthesis. In addition, it can also be used as a C- terminal modification group to adjust the synthetic peptide chain to change its solubility and hydrophilicity.
The method of preparing Fmoc-.beta.-cyclopropyl-D-Ala-OH is generally obtained by chemical synthesis. Specific steps include reacting L-cyclopropylalanine with Fmoc-chloride to form Fmoc-.beta.-cyclopropyl-D-Ala-OH. The synthesis process requires safe operation, avoiding contact with skin and inhalation of harmful gases.
When using Fmoc-.beta.-When cyclopropyl-D-Ala-OH, certain safety precautions should be followed, including wearing personal protective equipment (such as laboratory gloves and face masks), ensuring that the operating area is well ventilated, and following correct operating procedures. In addition, the compound may cause harm to the environment, so appropriate disposal methods should be adopted when disposing of waste to meet environmental protection requirements.
Last Update：2024-04-09 20:52:54
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CAS: 170642-29-2
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CAS: 170642-29-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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